PRO-TECHS ANTIMICROBIAL SURFACE SPRAY, A UNIQUELY DURABLE, HIGHLY EFFECTIVE, EASY TO APPLY, SAFE PREVENTIVE REMEDY FOR ANTIBIOTIC-RESISTANT COMMUNITY-AQUIRED INFECTIONS

PRO-TECHS ANTIMICROBIAL SURFACE SPRAY, A UNIQUELY DURABLE, HIGHLY EFFECTIVE, EASY TO APPLY, SAFE PREVENTIVE REMEDY FOR ANTIBIOTIC-RESISTANT COMMUNITY-AQUIRED INFECTIONS

PRO-TECHS ANTIMICROBIAL SURFACE SPRAY, A UNIQUELY DURABLE, HIGHLY EFFECTIVE, EASY TO APPLY, SAFE PREVENTIVE REMEDY FOR ANTIBIOTIC-RESISTANT COMMUNITY-AQUIRED INFECTIONS

Sanford P. Benjamin, M.D.
Medical Director, American Antimicrobial, INC.
520-D Eagleton Downs Drive
Pineville, NC 2834
info@protechsusa.com
“We should look at methods to solve problems that are better than the methods that we use to create them”
…Albert Einstein

PRO-TECHS ANTIMICROBIAL SURFACE SPRAY, A UNIQUELY DURABLE,
HIGHLY EFFECTIVE, EASY TO APPLY, SAFE PREVENTIVE REMEDY FOR
ANTIBIOTIC-RESISTANT COMMUNITY-AQUIRED INFECTIONS

PRO-Techs Antimicrobial Agent, A Preventive Remedy For Community-
Acquired Infection (CAI)

The Problem
The major contributing factor for CAI is microorganism contamination of “high touch” surfaces in the home, workplace and public venues.

Community -acquired infections are caused primarily by Antibiotic-Resistant Organisms which are clinically dangerous and possibly lethal. The majority of CAI are caused by methicillin-resistant Staphylococcus (MRSA), 80% , and Clostridium difficile, with lesser numbers of antibiotic-resistant fungus, virus, mold and mildew.

In 2012 and 2014, two separate scientific studies reported in the American Journal of Infection Control revealed that, in more than 50 percent of the time, utilizing customary cleaning agents including bleach (chlorine), peroxide, copper, and non-bonding organosilanes, “high touch” surfaces were not adequately cleaned and were recontaminated within minutes to 3 hours. These customary disinfectants lack “staying power”.

PRO-Techs, The Remedy For CAI Durability and Microbe Kill Spectrum : a single application of PRO-Techs protects ALL hard and soft surfaces against ALL bacteria, including antibiotic-resistant bacteria, ALL virus, ALL fungus, mold and mildew for 3+ months on ALL hard surfaces and 12-18 months or more on ALL soft textile surfaces, despite surface cleaning and continuous use. PRO-Techs durability is due to an outer protective silicon oxide shell barrier plus additional proprietary strong covalent chemical bonding agents which anchor to the treated surfaces.

Non-Leaching: PRO-Techs does not migrate, diffuse, or dissolve when it is applied since it is anchored to the surface at the point of application, thus consistently maintaining maximum microbe kill concentration for 3+ months on hard surfaces and 12-18 months or more on soft textile surfaces.

Kill Mechanism: PRO-Techs microbe-kill mechanism is physical, not chemical, unlike usual and customary disinfectants. The PRO-Techs kill process is electrocution at the point of microbe contact with the surface. Microbe death is instantaneous. No microbe can survive electrocution. There is no transfer of energy with electrocution, thus the kill process continues unabated for months.

Disinfectant Environment: Usual and customary chemical-kill cleaning agents have a latent time period lapse prior to microbe kill during which antibiotic-susceptible bacteria change their DNA component (mutation) and transition to antibiotic-resistant microbes. PRO-Techs kill process has no latent period, kills instantaneously and prevents adaptation to mutant antibiotic-resistant “superbugs”.

Effectiveness: Scientifically measured hard and soft surface contamination is reduced by 98.6 to 99 percent, working 24 hours a day, seven days a week.

PRO-Techs Effectiveness

(1) Glendale, California Community Hospital/UCLA ICU : Pre-application baseline antibiotic• resistant bacterial contamination rate of 23 percent; a single day 1 PRO-Techs spray application on “high-touch” surfaces (bathrooms, food tray, shower floor, computers, telephones, bed position controls, countertops, door knobs, handles, light switches, etc.) was completed and weekly surface cultures were obtained over a 15 week period. At 7 weeks, there were ZERO positive cultures for antibiotic-resistant bacteria. At 8 weeks, a single culture from a fabric chair armrest in the ICU visitors waiting room was positive for Vancomycin-resistant Enterococcus, a dangerous and possibly life threatening organism. This was the only positive culture obtained in the 15 week study. The bacterial contamination rate was reduced from 23 percent to 1.5 percent (Reference 3).

(2) Durban University Department of Biotechnology, Durban South Africa: A four week trial using a single plastic Petri dish containing nutrient agar media for bacterial growth and reproduction was overlaid with a spray layer of PRO-Techs and challenged with a massive 10 million per ml. dose of Staphylococcus aureus organisms. On day 1 and the following weeks one through four, the bacterial count was ZERO, despite weekly challenges of megadoses of Staphylococcus aureus. In the opinion of the research authors, the results support the manufacturer’s claim of effective bacterial killing up to 12 months duration.

MICROBE KILL SPECTRUM : PRO-Techs kills ALL bacteria, including antibiotic-resistant bacteria, All fungus, All virus, All mold and algae and All single cell parasites. Eighty percent of antibiotic-resistant bacteria are methicillin-resistant Staphylococcus. Antibiotic-resistant fungus includes respiratory tract infections, ear infections, athlete’s foot in wet showers. Antibiotic-resistant virus includes Coronavirus, Influenza, Herpes virus, HIV/AIDS and Norovirus. Antibiotic-resistant mold and algae include skin infection in boaters. Antibiotic resistant parasites include food-borne illness and amoebiasis.

PRO-TECHS DOES NOT PROVIDE AN ENVIRONMENT FOR ANTIBIOTIC-RESISTANT “SUPER BUG” FORMATION. Customary chemical kill disinfectants applied to a surface require a time lapse of two to three minutes before their kill mechanism is effective. During that time lapse, bacteria adapt by changing their DNA structure and mutate into resistant “superbugs.” With PRO-Techs application, there is no time lapse since the bacterial kill is instantaneous.

PRO-TECHS SAFETY PROFILE

PRO-Techs antimicrobial agent is registered and approved by the strict standards of the Environmental Protection Agency (EPA) and the European Biocide Agency as safe, food-grade clean, non-toxic, non- polluting, non-irritating, non-flammable, non-allergenic, biodegradable and environmentally green. When applied to any hard or soft surface, the result is colorless, odorless, and does not change the surface appearance or texture. If and when PRO-Techs comes into contact with the skin, oral cavity or eyes, it is non-absorbed, non-irritating and non-allergenic. However, the EPA mandates that all disinfectant products must be labeled with a warning: Flush with soap and water for skin contact and flush with water for eye and mouth contact.

PRO-TECHS SAFETY VALIDATION STUDIES

PRO-Techs toxicity studies have been performed by the EPA, Dow Chemical, Indusco LTD and Stillmeadows Inc., an independent research laboratory, regarding skin toxicity, eye toxicity, and oral consumption toxicity of PRO-Techs. In terms of oral exposure in laboratory rats, PRO-Techs is 250 times less lethal than a single aspirin tablet in terms of eye contact safety in laboratory rabbits, a very strong 5 percent solution of PRO-Techs, 7 times stronger than the current commercial preparation, caused temporary minor eye irritation but no eye damage. In terms of skin contact with PRO-Techs, the product is not absorbed, not irritating, and non-allergenic. The PRO-Techs toxicity levels for skin, eye and oral cavity contact satisfy an EPA category IV of the lowest level of toxicity and the highest degree of safety
as tested by the EPA, Indusco LTD, Dow Chemical and Stillmeadows Inc, Toxicology and ANALYTICAL SERVICES.

High-Touch Surfaces at Risk for Contamination and Community-Acquired Infection

Homes/ Nursing Homes : Kitchens (food preparation, counters, refrigerator handles, sink faucets and sink)
Bathrooms: sink and faucets, toilet, cell phones, land line phones, computers, video games, remotes, sound system, door knobs, light switches, work-out equipment, Yoga pants, floor mats.
Work Place

Child care centers

Restaurants / Fast Food

Public Transportation, Trains, Airplanes

Locker Rooms

Clothing : underwear, socks, shoe insoles

Cruise ships

Hospitals

Door knobs and light switches Auditoriums and stadiums Drinking Fountains
Military Uniforms

Schools/ Universities / Colleges
The kitchen is the number one most polluted area in the house. Kitchen surface areas of concern include food preparation counters, water faucets, sink, refrigerator door handles, kitchen table and chairs. Bathroom high touch contaminated surfaces include water faucets, sink, wet shower floors, toilet seat, and toilet flush handle. The family room and/or children’s playroom are high risk targets for contamination of television remote controls, video game consoles, computer keyboards, computer mouse, high touch toy surfaces. Exercise equipment, including floor mats are high risk surfaces. High
touch door knobs, light switches, and telephones pose an ever-present danger.

Home:

PRO-Techs Application Sites to Prevent CAI

• Kitchen and Bathrooms most vulnerable

• Window coverings

• Computers, telephones, tv remotes

• Door knobs, light switches

• Ocean cruises, casinos

• Airlines, buses, trains

• Nursing homes

• Locker rooms, fitness centers

• Schools, Colleges, Universities

• Auditorium, theaters, stadiums

• Workout clothes

• Fast Food / Cafeteria, Restaurants

Developing new antibiotics takes pharmaceutical companies more than ten years and costs over 2.5 billion dollars and thus far has failed. Without new and effective antibiotics, CDC data projects approximately 10 million acquired infections which kill approximately 500,000 people in the US on an
annual basis by the year 2050.

Influenza (flu)
Common Cold (Rhinovirus)
Community-Acquired Infections
COVID-19 (Coronavirus), (pneumonia) MRSA (wound infections)
Streptococcus (sore throat, pneumonia)
Norovirus, E-Coli, C-difficile (food poisoning, gastroenteritis) Hepatitis C (liver disease)
HIV (immune deficiency)
Mycoplasma, Chlamydia (pneumonia in children and young adults) Legionella (pneumonia)
Pseudomonas (hot tubs)
Tinea Pedis (athletes foot, shower floors) Mold and Mildew (asthma, lung disease)

PRO-TECHS KILL MECHANISM
PRO-Techs kill mechanism is physical, not chemical.
Microorganism cell membranes are all negatively charged and are attracted to the positive electric charged surface of the PRO-Techs antimicrobial agent.
The microbe cell membranes are punctured and impaled by the vertically aligned 18-carbon “bed of microswords the first phase of cell death.

The nitrogen-positive electric charge on the PRO-Techs molecule is directed at the punctured and impaled microorganisms with resultant electrocution and explosion of the target, the second and final phase of cell death. Electrocution does not provided an environment for mutant “superbug” antibiotic-resistant adaptive organisms since the kill is instantaneous and there is no time lapse. There is no transfer of energy with the electrical kill mechanism, thus the process continues to work indefinitely at full strength.

Benefits of PRO-Techs Spray Application:
1. Easy to apply.
2. Colorless, odorless and does not change the appearance or texture of the surface.
3. Improves public health in the best interests of the community.
4. Does not provide an opportunity for antibiotic-resistant “superbugs” to survive on surfaces.
5. PRO-Techs is cost efficient and quality effective.
6. PRO-Techs is safe, non-flammable and biodegradable.
7. Expert healthcare professionals have long been convinced that one ounce of prevention is worth more than a pound of cure. Since there is no optimal therapy for antibiotic-resistant microorganism infections, applications of PRO-Techs will provide substantial reduction of community-acquired infections; approximating 70 to 100 %.

Bottom Line
Antibiotic-resistant microbes infect approximately 3 million Americans on a yearly basis and the trend is increasing, according to the Center for Disease Control and Prevention and kill 162,000 for a mortality rate of 5 percent.

CONCLUSION

EXPERT HEALTH CARE PROFESSIONALS HAVE LONG BEEN CONVINCED THAT ONE OUNCE OF PREVENTION IS
WORTH MUCH MORE THAN ONE POUND OF CURE.

REFERENCES

1. Carling, P .C. et al. Evaluation hygiene in health care settings; what you do not know can harm your patients. American Journal of Infection control., vol. 38: 541-550, 2010.
2. Attaway, H.H. et al. Intrinsic bacterial burden associated with ICU hospital beds; effects of disinfection on population recovery and migration of potential infection . risk. American Journal of Infection Control, vol. 40: 907-912. 2012.
3. Tamimi., A.H. et al. Long term efficacy of a self-disinfecting coating in a 24 bed intensive care unit. American Journal of Infection Control, vol. 42:1178-1181. 2014
4. Faculty of Applied Sciences, Department of Biotechnology, Durban University (South Africa}.

Report on antibacterial effectiveness of PROTECHS antimicrobial. July, 2016.

5. Dow Corning {EPA MRID) #4038520

6. IndusCo LTD# OCSPP870.1100

7. lndusCo LTD #19734-15

8. Stillmeadows Corp. #4263-98

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